Selank
A Russian-developed synthetic heptapeptide registered as an anxiolytic in Russia โ with consistent animal data and small human trials, but no independent replication outside Russian research groups
Peptides targeting cognition, mood, anxiety, and sleep. Cerebrolysin is approved in many countries for stroke and dementia; Selank and Semax are Russian-registered for anxiety/cognition; DSIP has thin modern evidence despite the name. Quality and approval status differ widely.
A Russian-developed synthetic heptapeptide registered as an anxiolytic in Russia โ with consistent animal data and small human trials, but no independent replication outside Russian research groups
A Russian-developed synthetic heptapeptide registered for stroke and neurological disorders in Russia โ with genuine human clinical data, but almost entirely from Russian research groups and with no independent Western replication
Nine-amino-acid peptide first isolated in 1977 from rabbit cerebral venous blood during delta sleep. Modest human trial evidence for sleep and stress modulation.
Mixture of low-molecular-weight peptides and amino acids derived from purified porcine brain protein. Approved in many countries for stroke and dementia; evidence is mixed.