Epitalon
A synthetic tetrapeptide from pineal extract that activates telomerase in cell culture and extends mouse lifespan in one Russian lab — with almost no independent human evidence
Longevity & Anti-Aging Peptides
Peptides popularly marketed for longevity — a category where hype heavily outpaces evidence. Epitalon comes from Soviet-era pineal research; MK-677 raises IGF-1 but has cardiovascular signals in older adults. No peptide has demonstrated extended human lifespan in rigorous trials.
Peptides in this category
MOTS-c: Mitochondrial-Derived Peptide
Sixteen-amino-acid peptide encoded within the 12S rRNA region of mitochondrial DNA. Pre-clinical evidence for metabolic and longevity effects.
MK-677 (Ibutamoren): Oral Ghrelin Mimetic / GH Secretagogue
Oral, once-daily non-peptide ghrelin receptor agonist. Raises GH and IGF-1 but failed Phase 3 for sarcopenia; not an approved medicine.